Francesco "Frank" Lanza (died 1937) was the founder of the San Francisco crime family.

The San Francisco Crime Family was formed after the end of a gang war that started in 1928. Many street gangs were in a bloody battle to control bootlegging in the city. Francesco "Frank" Lanza was the leader of the toughest gang and became the first mob boss after the war ended in 1932. His family controlled loansharking, gambling, prostitution, narcotics and bootlegging. Lanza operated the San Francisco Fisherman's wharf with his business partner. His partner Giuseppe Alioto also found the International Fish Company. On July 14, 1937 Lanza died of natural causes at the age of 54. His son, James Lanza, would later take over as boss of the family.

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